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Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err along the side of caution and permit the FDA do its job and demand some research be done so the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on their medications. Researchers found out that participants taking this drug for a year, lost weight within 4 weeks and have kept the weight off through the 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more effective and safer. Combo-pilling may be the newest fad or even better the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that since right now there are no long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise blood pressure levels and heartrate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. An independent report published by Gant Daily in April also stated that naltrexone also utilizes kleptomaniacs and gambling addicts, as well. Citing research in the University of Minnesota School of Medicine, Gant Daily reported that the drug conditions kleptomaniacs and chronic gamblers just like with alcohol and opioid addicts'by blocking the effects of endorphins, that this brain releases when experiencing craving or compulsions.