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Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that creates them prone to benefit from naltrexone, in contrast to about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are currently available online ( within the journal Neuropsychopharmacology and will be published in the upcoming print edition in the journal. Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you should err assisting caution and permit the FDA do its job and demand some research be done in order that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on their medications. Researchers found out that participants investing in this drug to get a year, dropped a few pounds within 4 weeks and have kept the body weight off through the entire 56 weeks from the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular could be the fact that as of right now there are no long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure levels and pulse rate, and mustn't be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. A pyromaniac, with both psychiatric and medical therapy, can nonetheless be treated. It is best completed with behavioral therapy. Psychotherapy treatment alongside behavior modification is regarded as the frequently used treatment. Based on the study of Jon Grant, a combination treatment of drugs and behavioral therapy was discovered to be successful for pyromania. The usage of serotonin reuptake inhibitors can be beneficial in controlling the impulsive behavior with the patient like other impulse control disorder. Also of great help for the patient are medications including Lithium, naltrexone, (ReVia), fluoxetine (Prozac), citalopram (Celexa), paroxetene (Paxil), along with other antidepressants.