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Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err along the side of caution and permit the FDA do its job and demand some study be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on the medications. Researchers discovered that participants investing in this drug for a year, dropped a few pounds within one month and have kept the extra weight off during the entire 56 weeks of the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of multiple active ingredient, which might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular could be the fact that at the time of right now there aren't any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise blood pressure level and heartrate, and really should not be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.