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Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation which makes them more likely to benefit from naltrexone, in comparison with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are currently available online ( in the journal Neuropsychopharmacology and you will be published in the upcoming print edition in the journal. Using two separate drugs to shed pounds can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err to the side of caution and allow the FDA do its job and demand some research be done so your public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on their medications. Researchers found that participants investing in this drug for any year, dropped a few pounds within 4 weeks and have kept the body weight off through the 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, which may make them more effective and safer. Combo-pilling will be the newest fad or also the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that as of right now there aren't long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug may also raise blood pressure and heartbeat, and shouldn't be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. Other people who should avoid using Contrave are patients suffering from bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave mustn't be prescribed for girls who are pregnant or looking to become pregnant.