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Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err along the side of caution and permit the FDA do its job and demand some study be done so the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on their own medications. Researchers found out that participants investing in this drug for any year, dropped a few pounds within four weeks and have kept the load off throughout the 56 weeks with the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which might be made up of many active ingredient, which can make them far better and safer. Combo-pilling will be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular may be the fact that at the time of right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug could also raise blood pressure level and heartrate, and shouldn't be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients to the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. 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