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Suboxone allows a whole new approach. Using two separate drugs to shed weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people that go through it one should err on the side of caution and allow FDA do its job and demand some research be done so the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on the medications. Researchers found that participants using this drug for a year, lost weight within 4 weeks and have kept the body weight off through the 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, that might make them more efficient and safer. Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that at the time of right now there aren't long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise hypertension and heart rate, and really should not be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heartrate and must not used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.