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Suboxone allows a new approach. Using two separate drugs to lose weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err along the side of caution and let the FDA do its job and demand some research be done so your public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers found that participants using this drug for a year, lost weight within 4 weeks and have kept the extra weight off throughout the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer. Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular could be the fact that since right now there aren't long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug can also raise blood pressure and heart rate, and must not be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high hypertension, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. 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